منابع مشابه
vasopressin and septic shock
septic shock continues to be one of the leading causes of death in the intensive care units. when the shock state persists after adequate fluid resuscitation, vasopressor therapy is required to improve and maintain adequate tissue/organ perfusion in an attempt to improve survival and prevent the development of multiple organ dysfunction and failure. various studies have suggested that exogeno...
متن کاملVasopressin in septic shock
Vasopressin (also known as antidiuretic hormone) is a nonapeptide produced in the paraventricular and supraoptic nuclei of the hypothalamaus and released from the posterior pituitary. It has two distinct roles that underlie its two names. In health, its main effect is to act in the control of osmolarity. Stimulation of vasopressin receptors (V2) in the distal convoluted tubule of the kidney res...
متن کاملSeptic shock--vasopressin, norepinephrine, and urgency.
Septic shock is one of the most challenging problems in critical care medicine. Shock due to sepsis accounts for many of the deaths in medical and surgical intensive care units.1-4 It is estimated that septic shock results in approximately 215,000 deaths per year in the United States, a number similar to the number of deaths from acute myocardial infarction. However, the two disorders are not s...
متن کاملThe Septic Shock 3.0 Definition and Trials: A Vasopressin and Septic Shock Trial Experience.
OBJECTIVES The Septic Shock 3.0 definition could alter treatment comparisons in randomized controlled trials in septic shock. Our first hypothesis was that the vasopressin versus norepinephrine comparison and 28-day mortality of patients with Septic Shock 3.0 definition (lactate > 2 mmol/L) differ from vasopressin versus norepinephrine and mortality in Vasopressin and Septic Shock Trial. Our se...
متن کاملDear vasopressin, where is your place in septic shock?
Cardiovascular failure is one of the central therapeutic problems in patients with severe infection. Although norepinephrine is a potent and, in most cases, highly effective vasopressor agent, very high dosages leading to significant side effects can be necessary to stabilize advanced shock. As a supplementary vasopressor, arginine vasopressin can reverse hemodynamic failure and significantly d...
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ژورنال
عنوان ژورنال: Journal of the Intensive Care Society
سال: 2011
ISSN: 1751-1437
DOI: 10.1177/175114371101200105